This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1qbq

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1qbq" [edit=sysop:move=sysop])
Current revision (13:29, 13 March 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1qbq.png|left|200px]]
 
-
{{STRUCTURE_1qbq| PDB=1qbq | SCENE= }}
+
==STRUCTURE OF RAT FARNESYL PROTEIN TRANSFERASE COMPLEXED WITH A CVIM PEPTIDE AND ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID.==
-
 
+
<StructureSection load='1qbq' size='340' side='right'caption='[[1qbq]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-
===STRUCTURE OF RAT FARNESYL PROTEIN TRANSFERASE COMPLEXED WITH A CVIM PEPTIDE AND ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID.===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1qbq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QBQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QBQ FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_9843427}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HFP:ALPHA-HYDROXYFARNESYLPHOSPHONIC+ACID'>HFP</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qbq OCA], [https://pdbe.org/1qbq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qbq RCSB], [https://www.ebi.ac.uk/pdbsum/1qbq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qbq ProSAT]</span></td></tr>
-
[[1qbq]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QBQ OCA].
+
</table>
-
 
+
== Function ==
-
==Reference==
+
[https://www.uniprot.org/uniprot/FNTA_RAT FNTA_RAT] Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Through RAC1 prenylation and activation may positively regulate neuromuscular junction development downstream of MUSK (By similarity).
-
<ref group="xtra">PMID:009843427</ref><ref group="xtra">PMID:017918965</ref><references group="xtra"/>
+
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qb/1qbq_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qbq ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
-
[[Category: Beese, L. S.]]
+
[[Category: Beese LS]]
-
[[Category: Bond, R.]]
+
[[Category: Bond R]]
-
[[Category: Le, H. V.]]
+
[[Category: Le HV]]
-
[[Category: Schwartz, J.]]
+
[[Category: Schwartz J]]
-
[[Category: Strickland, C. L.]]
+
[[Category: Strickland CL]]
-
[[Category: Syto, R.]]
+
[[Category: Syto R]]
-
[[Category: Wang, L.]]
+
[[Category: Wang L]]
-
[[Category: Weber, P. C.]]
+
[[Category: Weber PC]]
-
[[Category: Windsor, W. T.]]
+
[[Category: Windsor WT]]
-
[[Category: Wu, Z.]]
+
[[Category: Wu Z]]
-
[[Category: Alpha-alpha-barrel helical crescent]]
+
-
[[Category: Transferase]]
+

Current revision

STRUCTURE OF RAT FARNESYL PROTEIN TRANSFERASE COMPLEXED WITH A CVIM PEPTIDE AND ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID.

PDB ID 1qbq

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1qbq"
Personal tools