This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1q9j
From Proteopedia
(Difference between revisions)
m (Protected "1q9j" [edit=sysop:move=sysop]) |
|||
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:1q9j.png|left|200px]] | ||
| - | + | ==Structure of polyketide synthase associated protein 5 from Mycobacterium tuberculosis== | |
| - | + | <StructureSection load='1q9j' size='340' side='right'caption='[[1q9j]], [[Resolution|resolution]] 2.75Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1q9j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q9J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q9J FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q9j OCA], [https://pdbe.org/1q9j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q9j RCSB], [https://www.ebi.ac.uk/pdbsum/1q9j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q9j ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1q9j TOPSAN]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1q9j]] is a 2 chain structure with sequence from [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/PAPA5_MYCTU PAPA5_MYCTU] Catalyzes diesterification of phthiocerol and phthiodiolone with mycocerosic acids, the final step in the phthiocerol and phthiodiolone dimycocerosate esters (PDIM) synthesis. Can directly transfer the mycocerosate bound to the mycocerosic acid synthase (mas) onto the substrate alcohols. Is also able to catalyze acyl transfer using various nucleophiles as acceptors and several acyl-CoA thioesters as donors in vitro; preference is observed for saturated medium chain alcohols and long chain acyl-CoA thioesters.<ref>PMID:15070765</ref> <ref>PMID:15749014</ref> | |
| - | == | + | == Evolutionary Conservation == |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [ | + | Check<jmol> |
| - | [ | + | <jmolCheckbox> |
| - | [ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q9/1q9j_consurf.spt"</scriptWhenChecked> |
| - | [ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [ | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [[ | + | </jmolCheckbox> |
| - | [ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q9j ConSurf]. |
| - | [[ | + | <div style="clear:both"></div> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
| - | [[Category: | + | [[Category: Buglino J]] |
| - | [[Category: | + | [[Category: Burley SK]] |
| - | [[Category: | + | [[Category: Lima CD]] |
| - | [[Category: | + | [[Category: Onwueme KC]] |
| - | [[Category: | + | [[Category: Quadri LE]] |
| - | + | ||
Current revision
Structure of polyketide synthase associated protein 5 from Mycobacterium tuberculosis
| |||||||||||
