1pzw
From Proteopedia
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| - | [[Image:1pzw.png|left|200px]] | ||
| - | + | ==Crystal structure of the zinc finger associated domain of the Drosophila transcription factor Grauzone== | |
| - | + | <StructureSection load='1pzw' size='340' side='right'caption='[[1pzw]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1pzw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PZW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PZW FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pzw OCA], [https://pdbe.org/1pzw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pzw RCSB], [https://www.ebi.ac.uk/pdbsum/1pzw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pzw ProSAT]</span></td></tr> |
| - | [[1pzw]] is a 1 chain structure with sequence from [ | + | </table> |
| - | + | == Function == | |
| - | == | + | [https://www.uniprot.org/uniprot/GRAU_DROME GRAU_DROME] Transcription factor essential for the completion of meiosis in oocytes. Grauzone binds to the promoter region of cort via the zf-AD domain and activates cort expression in ovaries.<ref>PMID:10683177</ref> <ref>PMID:10924478</ref> |
| - | < | + | == Evolutionary Conservation == |
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pz/1pzw_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pzw ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
| - | [[Category: Bourenkov | + | [[Category: Large Structures]] |
| - | [[Category: Chung | + | [[Category: Bourenkov GP]] |
| - | [[Category: Jaeckle | + | [[Category: Chung H-R]] |
| - | [[Category: Jauch | + | [[Category: Jaeckle H]] |
| - | [[Category: Reidt | + | [[Category: Jauch R]] |
| - | [[Category: Urlaub | + | [[Category: Reidt U]] |
| - | [[Category: Wahl | + | [[Category: Urlaub H]] |
| - | + | [[Category: Wahl MC]] | |
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Current revision
Crystal structure of the zinc finger associated domain of the Drosophila transcription factor Grauzone
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