1q48

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[[Image:1q48.png|left|200px]]
 
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{{STRUCTURE_1q48| PDB=1q48 | SCENE= }}
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==Solution NMR Structure of The Haemophilus Influenzae Iron-Sulfur Cluster Assembly Protein U (IscU) with Zinc Bound at the Active Site. Northeast Structural Genomics Consortium Target IR24. This protein is not apo, it is a model without zinc binding constraints.==
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<StructureSection load='1q48' size='340' side='right'caption='[[1q48]]' scene=''>
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===Solution NMR Structure of The Haemophilus Influenzae Iron-Sulfur Cluster Assembly Protein U (IscU) with Zinc Bound at the Active Site. Northeast Structural Genomics Consortium Target IR24. This protein is not apo, it is a model without zinc binding constraints.===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1q48]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q48 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q48 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15522305}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q48 OCA], [https://pdbe.org/1q48 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q48 RCSB], [https://www.ebi.ac.uk/pdbsum/1q48 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q48 ProSAT], [https://www.topsan.org/Proteins/NESGC/1q48 TOPSAN]</span></td></tr>
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==About this Structure==
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</table>
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[[1q48]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q48 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/ISCU_HAEIN ISCU_HAEIN] A scaffold on which IscS assembles Fe-S clusters. Subsequently gives the nascent cluster to other proteins. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (By similarity).
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==Reference==
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== Evolutionary Conservation ==
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<ref group="xtra">PMID:015522305</ref><references group="xtra"/>
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q4/1q48_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q48 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Haemophilus influenzae]]
[[Category: Haemophilus influenzae]]
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[[Category: Acton, T B.]]
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[[Category: Large Structures]]
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[[Category: Cort, J R.]]
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[[Category: Acton TB]]
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[[Category: Kennedy, M A.]]
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[[Category: Cort JR]]
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[[Category: Montelione, G T.]]
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[[Category: Kennedy MA]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Montelione GT]]
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[[Category: Ramelot, T A.]]
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[[Category: Ramelot TA]]
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[[Category: Shastry, R.]]
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[[Category: Shastry R]]
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[[Category: Xiao, R.]]
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[[Category: Xiao R]]
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[[Category: 3 beta strand]]
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[[Category: 4 alpha helix]]
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[[Category: Iron-sulfur cluster binding]]
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[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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[[Category: Three conserved cy]]
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[[Category: Unknown function]]
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Current revision

Solution NMR Structure of The Haemophilus Influenzae Iron-Sulfur Cluster Assembly Protein U (IscU) with Zinc Bound at the Active Site. Northeast Structural Genomics Consortium Target IR24. This protein is not apo, it is a model without zinc binding constraints.

PDB ID 1q48

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