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1q8d
From Proteopedia
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| - | [[Image:1q8d.png|left|200px]] | ||
| - | + | ==The crystal structure of GDNF family co-receptor alpha 1 domain 3== | |
| - | + | <StructureSection load='1q8d' size='340' side='right'caption='[[1q8d]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1q8d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q8D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q8D FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q8d OCA], [https://pdbe.org/1q8d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q8d RCSB], [https://www.ebi.ac.uk/pdbsum/1q8d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q8d ProSAT]</span></td></tr> |
| - | [[1q8d]] is a 1 chain structure with sequence from [ | + | </table> |
| - | + | == Function == | |
| - | == | + | [https://www.uniprot.org/uniprot/GFRA1_RAT GFRA1_RAT] Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. |
| - | < | + | == Evolutionary Conservation == |
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q8/1q8d_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q8d ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| - | [[Category: Bespalov | + | [[Category: Bespalov MM]] |
| - | [[Category: Goldman | + | [[Category: Goldman A]] |
| - | [[Category: Leppanen | + | [[Category: Leppanen VM]] |
| - | [[Category: Merits | + | [[Category: Merits A]] |
| - | [[Category: Puurand | + | [[Category: Puurand U]] |
| - | [[Category: Runeberg-Roos | + | [[Category: Runeberg-Roos P]] |
| - | [[Category: Saarma | + | [[Category: Saarma M]] |
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Current revision
The crystal structure of GDNF family co-receptor alpha 1 domain 3
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