1tgy
From Proteopedia
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| - | [[Image:1tgy.gif|left|200px]]<br /><applet load="1tgy" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1tgy, resolution 2.20Å" /> | ||
| - | '''Structure of E. coli Uridine Phosphorylase complexed with uracil and ribose 1-phosphate'''<br /> | ||
| - | == | + | ==Structure of E. coli Uridine Phosphorylase complexed with uracil and ribose 1-phosphate== |
| - | + | <StructureSection load='1tgy' size='340' side='right'caption='[[1tgy]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | [ | + | == Structural highlights == |
| - | + | <table><tr><td colspan='2'>[[1tgy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TGY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TGY FirstGlance]. <br> | |
| - | [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=R1P:RIBOSE-1-PHOSPHATE'>R1P</scene>, <scene name='pdbligand=URA:URACIL'>URA</scene></td></tr> | |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tgy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tgy OCA], [https://pdbe.org/1tgy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tgy RCSB], [https://www.ebi.ac.uk/pdbsum/1tgy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tgy ProSAT]</span></td></tr> |
| - | [[ | + | </table> |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/UDP_ECOLI UDP_ECOLI] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | [ | + | Check<jmol> |
| - | [[ | + | <jmolCheckbox> |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tg/1tgy_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tgy ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| + | *[[Uridine phosphorylase 3D structures|Uridine phosphorylase 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Begley TP]] | ||
| + | [[Category: Bu W]] | ||
| + | [[Category: Ealick SE]] | ||
| + | [[Category: Sanders JM]] | ||
| + | [[Category: Settembre EC]] | ||
Current revision
Structure of E. coli Uridine Phosphorylase complexed with uracil and ribose 1-phosphate
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