1suw

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[[Image:1suw.png|left|200px]]
 
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{{STRUCTURE_1suw| PDB=1suw | SCENE= }}
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==Crystal structure of a NAD kinase from Archaeoglobus fulgidus in complex with its substrate and product: Insights into the catalysis of NAD kinase==
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<StructureSection load='1suw' size='340' side='right'caption='[[1suw]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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===Crystal structure of a NAD kinase from Archaeoglobus fulgidus in complex with its substrate and product: Insights into the catalysis of NAD kinase===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1suw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SUW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SUW FirstGlance]. <br>
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{{ABSTRACT_PUBMED_16242716}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1suw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1suw OCA], [https://pdbe.org/1suw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1suw RCSB], [https://www.ebi.ac.uk/pdbsum/1suw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1suw ProSAT], [https://www.topsan.org/Proteins/BSGC/1suw TOPSAN]</span></td></tr>
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[[1suw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SUW OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/NADK_ARCFU NADK_ARCFU] Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.<ref>PMID:16242716</ref>
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<ref group="xtra">PMID:016242716</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/su/1suw_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1suw ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Archaeoglobus fulgidus]]
[[Category: Archaeoglobus fulgidus]]
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[[Category: Adams, P D.]]
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[[Category: Large Structures]]
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[[Category: BSGC, Berkeley Structural Genomics Center.]]
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[[Category: Adams PD]]
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[[Category: Kim, R.]]
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[[Category: Kim R]]
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[[Category: Kim, S H.]]
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[[Category: Kim S-H]]
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[[Category: Liu, J.]]
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[[Category: Liu J]]
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[[Category: Lou, Y.]]
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[[Category: Lou Y]]
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[[Category: Yokota, H.]]
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[[Category: Yokota H]]
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[[Category: Atp-nad kinase]]
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[[Category: Berkeley structural genomics center]]
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[[Category: Bsgc structure funded by nih]]
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[[Category: Nad]]
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[[Category: Nadk]]
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[[Category: Nadp]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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[[Category: Transferase]]
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Current revision

Crystal structure of a NAD kinase from Archaeoglobus fulgidus in complex with its substrate and product: Insights into the catalysis of NAD kinase

PDB ID 1suw

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