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1r8g
From Proteopedia
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| - | [[Image:1r8g.png|left|200px]] | ||
| - | + | ==Structure and function of YbdK== | |
| - | + | <StructureSection load='1r8g' size='340' side='right'caption='[[1r8g]], [[Resolution|resolution]] 2.15Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1r8g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R8G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R8G FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r8g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r8g OCA], [https://pdbe.org/1r8g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r8g RCSB], [https://www.ebi.ac.uk/pdbsum/1r8g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r8g ProSAT]</span></td></tr> |
| - | [[1r8g]] is a 2 chain structure with sequence from [ | + | </table> |
| - | + | == Function == | |
| - | == | + | [https://www.uniprot.org/uniprot/GCS2_ECOLI GCS2_ECOLI] ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity. However, because of the low catalytic rate, the question remains whether L-cysteine is the actual biological substrate.[HAMAP-Rule:MF_01609]<ref>PMID:15211520</ref> |
| - | < | + | == Evolutionary Conservation == |
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r8/1r8g_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r8g ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Doseeva | + | [[Category: Large Structures]] |
| - | [[Category: Herzberg | + | [[Category: Doseeva V]] |
| - | [[Category: Howard | + | [[Category: Herzberg O]] |
| - | [[Category: Krajewski | + | [[Category: Howard A]] |
| - | [[Category: Lehmann | + | [[Category: Krajewski W]] |
| - | [[Category: Pullalarevu | + | [[Category: Lehmann C]] |
| - | + | [[Category: Pullalarevu S]] | |
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Current revision
Structure and function of YbdK
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