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1sg4
From Proteopedia
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| - | [[Image:1sg4.png|left|200px]] | ||
| - | + | ==Crystal structure of human mitochondrial delta3-delta2-enoyl-CoA isomerase== | |
| - | + | <StructureSection load='1sg4' size='340' side='right'caption='[[1sg4]], [[Resolution|resolution]] 1.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1sg4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SG4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SG4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO8:OCTANOYL-COENZYME+A'>CO8</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sg4 OCA], [https://pdbe.org/1sg4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sg4 RCSB], [https://www.ebi.ac.uk/pdbsum/1sg4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sg4 ProSAT]</span></td></tr> |
| - | [[1sg4]] is a 3 chain structure with sequence from [ | + | </table> |
| - | + | == Function == | |
| - | == | + | [https://www.uniprot.org/uniprot/ECI1_HUMAN ECI1_HUMAN] Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. |
| - | < | + | == Evolutionary Conservation == |
| - | [[ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sg/1sg4_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sg4 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Hiltunen JK]] |
| - | [[Category: | + | [[Category: Mursula AM]] |
| - | [[Category: | + | [[Category: Novikov DK]] |
| - | [[Category: | + | [[Category: Partanen ST]] |
| - | [[Category: | + | [[Category: Popov AN]] |
| - | [[Category: | + | [[Category: Wierenga RK]] |
| - | + | ||
Current revision
Crystal structure of human mitochondrial delta3-delta2-enoyl-CoA isomerase
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