1s3c

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[[Image:1s3c.png|left|200px]]
 
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{{STRUCTURE_1s3c| PDB=1s3c | SCENE= }}
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==ARSENATE REDUCTASE C12S MUTANT FROM E. COLI==
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<StructureSection load='1s3c' size='340' side='right'caption='[[1s3c]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1s3c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S3C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S3C FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s3c OCA], [https://pdbe.org/1s3c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s3c RCSB], [https://www.ebi.ac.uk/pdbsum/1s3c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s3c ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ARSC1_ECOLX ARSC1_ECOLX] Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s3/1s3c_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s3c ConSurf].
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<div style="clear:both"></div>
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===ARSENATE REDUCTASE C12S MUTANT FROM E. COLI===
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==See Also==
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*[[Arsenate reductase 3D structures|Arsenate reductase 3D structures]]
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{{ABSTRACT_PUBMED_15295115}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[1s3c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S3C OCA].
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==Reference==
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<ref group="xtra">PMID:015295115</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: DeMel, S.]]
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[[Category: Large Structures]]
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[[Category: Edwards, B F.]]
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[[Category: DeMel S]]
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[[Category: Arsc]]
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[[Category: Edwards BF]]
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[[Category: Arsenate]]
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[[Category: Arsenite]]
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[[Category: Oxidoreductase]]
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[[Category: Reductase]]
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Current revision

ARSENATE REDUCTASE C12S MUTANT FROM E. COLI

PDB ID 1s3c

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