1sff
From Proteopedia
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| - | [[Image:1sff.png|left|200px]] | ||
| - | + | ==Structure of gamma-aminobutyrate aminotransferase complex with aminooxyacetate== | |
| + | <StructureSection load='1sff' size='340' side='right'caption='[[1sff]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1sff]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SFF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SFF FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IK2:4-DEOXY-4-ACETYLYAMINO-PYRIDOXAL-5-PHOSPHATE'>IK2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sff FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sff OCA], [https://pdbe.org/1sff PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sff RCSB], [https://www.ebi.ac.uk/pdbsum/1sff PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sff ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GABT_ECOLI GABT_ECOLI] Catalyzes the transfer of the amino group from gamma-aminobutyrate (GABA) to alpha-ketoglutarate (KG) to yield succinic semialdehyde (SSA).<ref>PMID:20639325</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sf/1sff_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sff ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Aminotransferase 3D structures|Aminotransferase 3D structures]] | |
| - | + | == References == | |
| - | + | <references/> | |
| - | + | __TOC__ | |
| - | [[ | + | </StructureSection> |
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| - | == | + | |
| - | < | + | |
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[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Carter | + | [[Category: Large Structures]] |
| - | [[Category: Fisher | + | [[Category: Carter RJ]] |
| - | [[Category: Langston | + | [[Category: Fisher AJ]] |
| - | [[Category: Liu | + | [[Category: Langston JA]] |
| - | [[Category: Peterson | + | [[Category: Liu W]] |
| - | [[Category: Toney | + | [[Category: Peterson PE]] |
| - | [[Category: Zhou | + | [[Category: Toney MD]] |
| - | + | [[Category: Zhou X]] | |
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Current revision
Structure of gamma-aminobutyrate aminotransferase complex with aminooxyacetate
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Categories: Escherichia coli | Large Structures | Carter RJ | Fisher AJ | Langston JA | Liu W | Peterson PE | Toney MD | Zhou X
