1s2m

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[[Image:1s2m.png|left|200px]]
 
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{{STRUCTURE_1s2m| PDB=1s2m | SCENE= }}
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==Crystal Structure of the DEAD box protein Dhh1p==
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<StructureSection load='1s2m' size='340' side='right'caption='[[1s2m]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1s2m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S2M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S2M FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s2m OCA], [https://pdbe.org/1s2m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s2m RCSB], [https://www.ebi.ac.uk/pdbsum/1s2m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s2m ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DHH1_YEAST DHH1_YEAST] ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export. Required for sporulation.<ref>PMID:9504907</ref> <ref>PMID:11780629</ref> <ref>PMID:12032091</ref> <ref>PMID:11696541</ref> <ref>PMID:12930949</ref> <ref>PMID:12730603</ref> <ref>PMID:15166134</ref> <ref>PMID:15703442</ref> <ref>PMID:15706350</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s2/1s2m_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s2m ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of the DEAD box protein Dhh1p===
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==See Also==
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*[[Helicase 3D structures|Helicase 3D structures]]
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{{ABSTRACT_PUBMED_15987810}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[1s2m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S2M OCA].
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</StructureSection>
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[[Category: Large Structures]]
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==Reference==
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<ref group="xtra">PMID:015987810</ref><references group="xtra"/>
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Cheng, Z.]]
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[[Category: Cheng Z]]
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[[Category: Song, H.]]
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[[Category: Song H]]
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[[Category: Atp-binding]]
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[[Category: Helicase]]
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[[Category: Rna binding protein]]
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[[Category: Rna-binding]]
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Current revision

Crystal Structure of the DEAD box protein Dhh1p

PDB ID 1s2m

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OCA

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