This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1s1j
From Proteopedia
(Difference between revisions)
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:1s1j.png|left|200px]] | ||
| - | + | ==Crystal Structure of ZipA in complex with indoloquinolizin inhibitor 1== | |
| + | <StructureSection load='1s1j' size='340' side='right'caption='[[1s1j]], [[Resolution|resolution]] 2.18Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1s1j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S1J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S1J FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.18Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IQZ:(12BS)-1,2,3,4,12,12B-HEXAHYDROINDOLO[2,3-A]QUINOLIZIN-7(6H)-ONE'>IQZ</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s1j OCA], [https://pdbe.org/1s1j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s1j RCSB], [https://www.ebi.ac.uk/pdbsum/1s1j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s1j ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ZIPA_ECOLI ZIPA_ECOLI] Interacts directly with the cell division protein FtsZ. Probable receptor for the septal ring structure, may anchor it to the inner-membrane.[HAMAP-Rule:MF_00509] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s1/1s1j_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s1j ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Cell division protein 3D structures|Cell division protein 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | [[ | + | |
| - | + | ||
| - | + | ||
| - | < | + | |
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Ding W]] |
| - | [[Category: | + | [[Category: Dushin EG]] |
| - | [[Category: | + | [[Category: Foreman KW]] |
| - | [[Category: Jenning | + | [[Category: Jenning LD]] |
| - | [[Category: Kenney | + | [[Category: Kenney CH]] |
| - | [[Category: Li | + | [[Category: Li Y]] |
| - | [[Category: Moghazeh | + | [[Category: Moghazeh SL]] |
| - | [[Category: Mosyak | + | [[Category: Mosyak L]] |
| - | [[Category: Peterson | + | [[Category: Peterson PJ]] |
| - | [[Category: | + | [[Category: Rush III TS]] |
| - | [[Category: | + | [[Category: Ruzin AV]] |
| - | [[Category: | + | [[Category: Sukhdeo MN]] |
| - | [[Category: | + | [[Category: Sutherland AG]] |
| - | [[Category: | + | [[Category: Tsao DH]] |
| - | [[Category: | + | [[Category: Tuckman M]] |
Current revision
Crystal Structure of ZipA in complex with indoloquinolizin inhibitor 1
| |||||||||||
Categories: Escherichia coli | Large Structures | Ding W | Dushin EG | Foreman KW | Jenning LD | Kenney CH | Li Y | Moghazeh SL | Mosyak L | Peterson PJ | Rush III TS | Ruzin AV | Sukhdeo MN | Sutherland AG | Tsao DH | Tuckman M

