1s1j
From Proteopedia
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- | [[Image:1s1j.png|left|200px]] | ||
- | + | ==Crystal Structure of ZipA in complex with indoloquinolizin inhibitor 1== | |
+ | <StructureSection load='1s1j' size='340' side='right'caption='[[1s1j]], [[Resolution|resolution]] 2.18Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[1s1j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S1J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S1J FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.18Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IQZ:(12BS)-1,2,3,4,12,12B-HEXAHYDROINDOLO[2,3-A]QUINOLIZIN-7(6H)-ONE'>IQZ</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s1j OCA], [https://pdbe.org/1s1j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s1j RCSB], [https://www.ebi.ac.uk/pdbsum/1s1j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s1j ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/ZIPA_ECOLI ZIPA_ECOLI] Interacts directly with the cell division protein FtsZ. Probable receptor for the septal ring structure, may anchor it to the inner-membrane.[HAMAP-Rule:MF_00509] | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s1/1s1j_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s1j ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
- | == | + | ==See Also== |
- | + | *[[Cell division protein 3D structures|Cell division protein 3D structures]] | |
- | + | __TOC__ | |
- | + | </StructureSection> | |
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- | [[ | + | |
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[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Ding W]] |
- | [[Category: | + | [[Category: Dushin EG]] |
- | [[Category: | + | [[Category: Foreman KW]] |
- | [[Category: Jenning | + | [[Category: Jenning LD]] |
- | [[Category: Kenney | + | [[Category: Kenney CH]] |
- | [[Category: Li | + | [[Category: Li Y]] |
- | [[Category: Moghazeh | + | [[Category: Moghazeh SL]] |
- | [[Category: Mosyak | + | [[Category: Mosyak L]] |
- | [[Category: Peterson | + | [[Category: Peterson PJ]] |
- | [[Category: | + | [[Category: Rush III TS]] |
- | [[Category: | + | [[Category: Ruzin AV]] |
- | [[Category: | + | [[Category: Sukhdeo MN]] |
- | [[Category: | + | [[Category: Sutherland AG]] |
- | [[Category: | + | [[Category: Tsao DH]] |
- | [[Category: | + | [[Category: Tuckman M]] |
Current revision
Crystal Structure of ZipA in complex with indoloquinolizin inhibitor 1
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Categories: Escherichia coli | Large Structures | Ding W | Dushin EG | Foreman KW | Jenning LD | Kenney CH | Li Y | Moghazeh SL | Mosyak L | Peterson PJ | Rush III TS | Ruzin AV | Sukhdeo MN | Sutherland AG | Tsao DH | Tuckman M