This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1t3j

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1t3j" [edit=sysop:move=sysop])
Current revision (08:35, 14 February 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1t3j.png|left|200px]]
 
-
{{STRUCTURE_1t3j| PDB=1t3j | SCENE= }}
+
==Mitofusin domain HR2 V686M/I708M mutant==
-
 
+
<StructureSection load='1t3j' size='340' side='right'caption='[[1t3j]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-
===Mitofusin domain HR2 V686M/I708M mutant===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1t3j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T3J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T3J FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_15297672}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t3j OCA], [https://pdbe.org/1t3j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t3j RCSB], [https://www.ebi.ac.uk/pdbsum/1t3j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t3j ProSAT]</span></td></tr>
-
==About this Structure==
+
</table>
-
[[1t3j]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T3J OCA].
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/MFN1_MOUSE MFN1_MOUSE] Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.<ref>PMID:12527753</ref> <ref>PMID:15297672</ref>
-
==Reference==
+
== Evolutionary Conservation ==
-
<ref group="xtra">PMID:015297672</ref><references group="xtra"/>
+
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t3/1t3j_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t3j ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Chan, D C.]]
+
[[Category: Chan DC]]
-
[[Category: Chen, H.]]
+
[[Category: Chen H]]
-
[[Category: Detmer, S A.]]
+
[[Category: Detmer SA]]
-
[[Category: Kaiser, J T.]]
+
[[Category: Kaiser JT]]
-
[[Category: Koshiba, T.]]
+
[[Category: Koshiba T]]
-
[[Category: McCaffery, J M.]]
+
[[Category: McCaffery JM]]
-
[[Category: Coiled coil antiparallel]]
+
-
[[Category: Dimer]]
+
-
[[Category: Membrane protein]]
+

Current revision

Mitofusin domain HR2 V686M/I708M mutant

PDB ID 1t3j

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1t3j"
Personal tools