1wbm

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[[Image:1wbm.png|left|200px]]
 
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{{STRUCTURE_1wbm| PDB=1wbm | SCENE= }}
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==HIV-1 protease in complex with symmetric inhibitor, BEA450==
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<StructureSection load='1wbm' size='340' side='right'caption='[[1wbm]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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===HIV-1 PROTEASE IN COMPLEX WITH SYMMETRIC INHIBITOR, BEA450===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1wbm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WBM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WBM FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11585446}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BLL:(2R,3R,4R,5R)-3,4-DIHYDROXY-N,N-BIS[(1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]-2,5-BIS(2-PHENYLETHYL)HEXANEDIAMIDE'>BLL</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wbm OCA], [https://pdbe.org/1wbm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wbm RCSB], [https://www.ebi.ac.uk/pdbsum/1wbm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wbm ProSAT]</span></td></tr>
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[[1wbm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WBM OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8Q3H0_9HIV1 Q8Q3H0_9HIV1]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wb/1wbm_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wbm ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Lindberg, J.]]
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[[Category: Large Structures]]
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[[Category: Unge, T.]]
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[[Category: Lindberg J]]
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[[Category: Aid]]
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[[Category: Unge T]]
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[[Category: Aspartyl protease]]
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[[Category: Dimer]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-inhibitor complex]]
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[[Category: Hydrolase/hydrolase inhibitor]]
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[[Category: Hydrolase/inhibitor]]
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[[Category: Protein-inhibitor complex]]
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Current revision

HIV-1 protease in complex with symmetric inhibitor, BEA450

PDB ID 1wbm

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