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1tzl

From Proteopedia

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[[Image:1tzl.png|left|200px]]
 
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{{STRUCTURE_1tzl| PDB=1tzl | SCENE= }}
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==Crystal Structure of Pyranose 2-Oxidase from the White-Rot Fungus Peniophora sp.==
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<StructureSection load='1tzl' size='340' side='right'caption='[[1tzl]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1tzl]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Peniophora_sp._SG Peniophora sp. SG]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TZL FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tzl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tzl OCA], [https://pdbe.org/1tzl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tzl RCSB], [https://www.ebi.ac.uk/pdbsum/1tzl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tzl ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/P2OX_PENSG P2OX_PENSG] Catalyzes the oxidation of various aldopyranoses and disaccharides on carbon-2 to the corresponding 2-keto sugars concomitant with the reduction of O(2) to H(2)O(2). Plays an important role in lignin degradation of wood rot fungi by supplying the essential cosubstrate H(2)O(2) for the ligninolytic peroxidases, lignin peroxidase and manganese-dependent peroxidase (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tz/1tzl_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tzl ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of Pyranose 2-Oxidase from the White-Rot Fungus Peniophora sp.===
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==See Also==
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*[[Pyranose oxidase|Pyranose oxidase]]
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{{ABSTRACT_PUBMED_15362852}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[1tzl]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Peniophora_sp._sg Peniophora sp. sg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZL OCA].
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[[Category: Peniophora sp. SG]]
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[[Category: Bannwarth M]]
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==Reference==
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[[Category: Bastian S]]
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<ref group="xtra">PMID:015362852</ref><references group="xtra"/>
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[[Category: Giffhorn F]]
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[[Category: Peniophora sp. sg]]
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[[Category: Heckmann-Pohl D]]
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[[Category: Pyranose oxidase]]
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[[Category: Schulz GE]]
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[[Category: Bannwarth, M.]]
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[[Category: Bastian, S.]]
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[[Category: Giffhorn, F.]]
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[[Category: Heckmann-Pohl, D.]]
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[[Category: Schulz, G E.]]
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[[Category: Glucose-methanol-choline family]]
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[[Category: Gmc oxidoreductase]]
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[[Category: Large inner cavity]]
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[[Category: Oxidoreductase]]
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Current revision

Crystal Structure of Pyranose 2-Oxidase from the White-Rot Fungus Peniophora sp.

PDB ID 1tzl

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