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1xm5
From Proteopedia
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| - | [[Image:1xm5.png|left|200px]] | ||
| - | + | ==Crystal structure of metal-dependent hydrolase ybeY from E. coli, Pfam UPF0054== | |
| - | + | <StructureSection load='1xm5' size='340' side='right'caption='[[1xm5]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1xm5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XM5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XM5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xm5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xm5 OCA], [https://pdbe.org/1xm5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xm5 RCSB], [https://www.ebi.ac.uk/pdbsum/1xm5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xm5 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1xm5 TOPSAN]</span></td></tr> |
| - | [[1xm5]] is a 4 chain structure with sequence from [ | + | </table> |
| - | + | == Function == | |
| - | == | + | [https://www.uniprot.org/uniprot/YBEY_ECOLI YBEY_ECOLI] Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. Acts together with the RNase R to eliminate defective 70S ribosomes, but not properly matured 70S ribosomes or individual subunits, by a process mediated specifically by the 30S ribosomal subunit. Involved in the processing of 16S, 23S and 5S rRNAs, with a particularly strong effect on maturation at both the 5'-and 3'-ends of 16S rRNA as well as maturation of the 5'-end of 23S and 5S rRNAs.<ref>PMID:20639334</ref> <ref>PMID:20807199</ref> <ref>PMID:23273979</ref> <ref>PMID:16511207</ref> |
| - | < | + | == Evolutionary Conservation == |
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xm/1xm5_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xm5 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Almo SC]] |
| - | [[Category: | + | [[Category: Burley SK]] |
| - | [[Category: Fedorov | + | [[Category: Fedorov AA]] |
| - | [[Category: | + | [[Category: Fedorov EV]] |
| - | [[Category: Ramagopal | + | [[Category: Ramagopal UA]] |
| - | [[Category: Shi | + | [[Category: Shi W]] |
| - | [[Category: Thirumuruhan | + | [[Category: Thirumuruhan R]] |
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Current revision
Crystal structure of metal-dependent hydrolase ybeY from E. coli, Pfam UPF0054
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