1x37

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[[Image:1x37.png|left|200px]]
 
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{{STRUCTURE_1x37| PDB=1x37 | SCENE= }}
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==Structure of Bacillus subtilis Lon protease SSD domain==
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<StructureSection load='1x37' size='340' side='right'caption='[[1x37]]' scene=''>
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===Structure of Bacillus subtilis Lon protease SSD domain===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1x37]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X37 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X37 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x37 OCA], [https://pdbe.org/1x37 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x37 RCSB], [https://www.ebi.ac.uk/pdbsum/1x37 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x37 ProSAT]</span></td></tr>
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[[1x37]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X37 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LON1_BACSU LON1_BACSU] ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity). Has been implicated in preventing sigma(G) activity under non-sporulation conditions.[HAMAP-Rule:MF_01973]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x3/1x37_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x37 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Endopeptidase La]]
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[[Category: Large Structures]]
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[[Category: Chen, C.]]
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[[Category: Chen C]]
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[[Category: Lee, Y L.]]
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[[Category: Lee YL]]
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[[Category: Lo, S C.]]
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[[Category: Lo SC]]
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[[Category: Lou, Y C.]]
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[[Category: Lou YC]]
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[[Category: Wang, I.]]
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[[Category: Wang I]]
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[[Category: Wu, S H.]]
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[[Category: Wu SH]]
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[[Category: Aaa+ superfamily]]
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[[Category: Hydrolase]]
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[[Category: Protease]]
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[[Category: Solution structure]]
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[[Category: Ssd domain]]
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Current revision

Structure of Bacillus subtilis Lon protease SSD domain

PDB ID 1x37

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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