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1u1z
From Proteopedia
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| - | [[Image:1u1z.png|left|200px]] | ||
| - | + | ==The Structure of (3R)-hydroxyacyl-ACP dehydratase (FabZ)== | |
| + | <StructureSection load='1u1z' size='340' side='right'caption='[[1u1z]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1u1z]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. The June 2007 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Fatty Acid Synthase'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2007_6 10.2210/rcsb_pdb/mom_2007_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U1Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U1Z FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u1z OCA], [https://pdbe.org/1u1z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u1z RCSB], [https://www.ebi.ac.uk/pdbsum/1u1z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u1z ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FABZ_PSEAE FABZ_PSEAE] Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u1/1u1z_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u1z ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | === | + | ==See Also== |
| - | + | *[[Beta-hydroxyacyl-acyl carrier protein dehydratase 3D structures|Beta-hydroxyacyl-acyl carrier protein dehydratase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
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| - | < | + | |
[[Category: Fatty Acid Synthase]] | [[Category: Fatty Acid Synthase]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Pseudomonas aeruginosa]] | [[Category: Pseudomonas aeruginosa]] | ||
[[Category: RCSB PDB Molecule of the Month]] | [[Category: RCSB PDB Molecule of the Month]] | ||
| - | [[Category: Dharamsi | + | [[Category: Dharamsi A]] |
| - | [[Category: Fiebig | + | [[Category: Fiebig KM]] |
| - | [[Category: Houston | + | [[Category: Houston S]] |
| - | [[Category: Kimber | + | [[Category: Kimber MS]] |
| - | [[Category: Lu | + | [[Category: Lu Y]] |
| - | [[Category: Martin | + | [[Category: Martin F]] |
| - | [[Category: Rock | + | [[Category: Rock CO]] |
| - | [[Category: Schmid | + | [[Category: Schmid M]] |
| - | [[Category: Vedadi | + | [[Category: Vedadi M]] |
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Current revision
The Structure of (3R)-hydroxyacyl-ACP dehydratase (FabZ)
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