1xxc
From Proteopedia
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- | [[Image:1xxc.png|left|200px]] | ||
- | + | ==C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR== | |
+ | <StructureSection load='1xxc' size='340' side='right'caption='[[1xxc]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[1xxc]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XXC FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xxc OCA], [https://pdbe.org/1xxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xxc RCSB], [https://www.ebi.ac.uk/pdbsum/1xxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xxc ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/ARGR_ECOLI ARGR_ECOLI] Negatively controls the expression of the four operons of arginine biosynthesis in addition to the carAB operon. Predominantly interacts with A/T residues in ARG boxes. It also binds to a specific site in cer locus. Thus it is essential for cer-mediated site-specific recombination in ColE1. It is necessary for monomerization of the plasmid ColE1. | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xx/1xxc_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xxc ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
- | == | + | ==See Also== |
- | + | *[[Arginine repressor 3D structures|Arginine repressor 3D structures]] | |
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | + | [[Category: Escherichia coli K-12]] | |
- | [[ | + | [[Category: Large Structures]] |
- | + | [[Category: Ghosh G]] | |
- | + | [[Category: Maas WK]] | |
- | < | + | [[Category: Sigler PB]] |
- | [[Category: Escherichia coli | + | [[Category: Van Duyne GD]] |
- | [[Category: | + | |
- | [[Category: Ghosh | + | |
- | [[Category: Maas | + | |
- | [[Category: Sigler | + | |
- | [[Category: | + |
Current revision
C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR
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