1we7

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[[Image:1we7.png|left|200px]]
 
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{{STRUCTURE_1we7| PDB=1we7 | SCENE= }}
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==Solution structure of Ubiquitin-like domain in SF3a120==
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<StructureSection load='1we7' size='340' side='right'caption='[[1we7]]' scene=''>
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===Solution structure of Ubiquitin-like domain in SF3a120===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1we7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WE7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WE7 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1we7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1we7 OCA], [https://pdbe.org/1we7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1we7 RCSB], [https://www.ebi.ac.uk/pdbsum/1we7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1we7 ProSAT], [https://www.topsan.org/Proteins/RSGI/1we7 TOPSAN]</span></td></tr>
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[[1we7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WE7 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SF3A1_MOUSE SF3A1_MOUSE] Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/we/1we7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1we7 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: He, F.]]
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[[Category: He F]]
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[[Category: Inoue, M.]]
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[[Category: Inoue M]]
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[[Category: Kigawa, T.]]
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[[Category: Kigawa T]]
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[[Category: Muto, Y.]]
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[[Category: Muto Y]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Shirouzu M]]
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[[Category: Shirouzu, M.]]
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[[Category: Terada T]]
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[[Category: Terada, T.]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S.]]
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[[Category: Gene regulation]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Sf3a120]]
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[[Category: Structural genomic]]
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[[Category: Ubiquitin-like domain]]
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Current revision

Solution structure of Ubiquitin-like domain in SF3a120

PDB ID 1we7

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