1uxc

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[[Image:1uxc.png|left|200px]]
 
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{{STRUCTURE_1uxc| PDB=1uxc | SCENE= }}
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==FRUCTOSE REPRESSOR DNA-BINDING DOMAIN, NMR, MINIMIZED STRUCTURE==
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<StructureSection load='1uxc' size='340' side='right'caption='[[1uxc]]' scene=''>
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===FRUCTOSE REPRESSOR DNA-BINDING DOMAIN, NMR, MINIMIZED STRUCTURE===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1uxc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UXC FirstGlance]. <br>
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{{ABSTRACT_PUBMED_9237914}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uxc OCA], [https://pdbe.org/1uxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uxc RCSB], [https://www.ebi.ac.uk/pdbsum/1uxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uxc ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1uxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UXC OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/CRA_ECOLI CRA_ECOLI] Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism. Activates transcription of genes encoding biosynthetic and oxidative enzymes (involved in Krebs cycle, glyoxylate shunt and gluconeogenesis, such as ppsA and fbp). Represses genes involved in sugar catabolism, such as fruB, pfkA, pykF and adhE. Binds asymmetrically to the two half-sites of its operator.<ref>PMID:16115199</ref> <ref>PMID:8195118</ref> <ref>PMID:8230205</ref> <ref>PMID:8550429</ref> <ref>PMID:8577250</ref> <ref>PMID:8858581</ref> <ref>PMID:9084760</ref> <ref>PMID:9371462</ref>
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==Reference==
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== Evolutionary Conservation ==
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<ref group="xtra">PMID:009237914</ref><ref group="xtra">PMID:015267926</ref><references group="xtra"/>
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Escherichia coli]]
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Check<jmol>
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[[Category: Bockmann, A.]]
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<jmolCheckbox>
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[[Category: Bonod-Bidaud, C.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ux/1uxc_consurf.spt"</scriptWhenChecked>
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[[Category: Cortay, J C.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Cozzone, A J.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Deleage, G.]]
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</jmolCheckbox>
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[[Category: Geourjon, C.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uxc ConSurf].
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[[Category: Lesage, A.]]
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<div style="clear:both"></div>
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[[Category: Montserret, R.]]
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== References ==
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[[Category: Negre, D.]]
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<references/>
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[[Category: Penin, F.]]
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__TOC__
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[[Category: Yang, Y.]]
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</StructureSection>
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[[Category: Dna-binding protein]]
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[[Category: Escherichia coli K-12]]
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[[Category: Fructose repressor]]
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[[Category: Large Structures]]
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[[Category: Laci family]]
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[[Category: Bockmann A]]
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[[Category: Transcription regulation]]
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[[Category: Bonod-Bidaud C]]
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[[Category: Cortay JC]]
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[[Category: Cozzone AJ]]
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[[Category: Deleage G]]
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[[Category: Geourjon C]]
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[[Category: Lesage A]]
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[[Category: Montserret R]]
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[[Category: Negre D]]
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[[Category: Penin F]]
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[[Category: Yang Y]]

Current revision

FRUCTOSE REPRESSOR DNA-BINDING DOMAIN, NMR, MINIMIZED STRUCTURE

PDB ID 1uxc

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