1tf7

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[[Image:1tf7.png|left|200px]]
 
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{{STRUCTURE_1tf7| PDB=1tf7 | SCENE= }}
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==Crystal Structure of Circadian Clock Protein KaiC==
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<StructureSection load='1tf7' size='340' side='right'caption='[[1tf7]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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===Crystal Structure of Circadian Clock Protein KaiC===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1tf7]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Synechococcus_sp. Synechococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TF7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TF7 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15304218}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tf7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tf7 OCA], [https://pdbe.org/1tf7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tf7 RCSB], [https://www.ebi.ac.uk/pdbsum/1tf7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tf7 ProSAT]</span></td></tr>
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[[1tf7]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Synechococcus_sp. Synechococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TF7 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KAIC_SYNE7 KAIC_SYNE7] Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction.<ref>PMID:9727980</ref> <ref>PMID:14709675</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tf/1tf7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tf7 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Circadian Clock Protein KaiC|Circadian Clock Protein KaiC]]
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*[[Circadian clock protein 3D structures|Circadian clock protein 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:015304218</ref><ref group="xtra">PMID:016628225</ref><references group="xtra"/>
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__TOC__
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[[Category: Synechococcus sp.]]
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</StructureSection>
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[[Category: Egli, M.]]
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[[Category: Large Structures]]
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[[Category: Johnson, C H.]]
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[[Category: Synechococcus sp]]
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[[Category: Mori, T.]]
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[[Category: Egli M]]
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[[Category: Pattanayek, R.]]
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[[Category: Johnson CH]]
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[[Category: Wang, J.]]
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[[Category: Mori T]]
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[[Category: Xu, Y.]]
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[[Category: Pattanayek R]]
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[[Category: Circadian clock protein]]
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[[Category: Wang J]]
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[[Category: Hexamer]]
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[[Category: Xu Y]]
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[[Category: Homohexamer]]
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Current revision

Crystal Structure of Circadian Clock Protein KaiC

PDB ID 1tf7

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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