1te2

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[[Image:1te2.png|left|200px]]
 
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{{STRUCTURE_1te2| PDB=1te2 | SCENE= }}
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==Putative Phosphatase Ynic from Escherichia coli K12==
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<StructureSection load='1te2' size='340' side='right'caption='[[1te2]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
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===Putative Phosphatase Ynic from Escherichia coli K12===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1te2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TE2 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PGA:2-PHOSPHOGLYCOLIC+ACID'>PGA</scene></td></tr>
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[[1te2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_o157:h7 Escherichia coli o157:h7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TE2 OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1te2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1te2 OCA], [https://pdbe.org/1te2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1te2 RCSB], [https://www.ebi.ac.uk/pdbsum/1te2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1te2 ProSAT], [https://www.topsan.org/Proteins/MCSG/1te2 TOPSAN]</span></td></tr>
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[[Category: Escherichia coli o157:h7]]
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</table>
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[[Category: Phosphoglycolate phosphatase]]
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== Function ==
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[[Category: Edwards, A.]]
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[https://www.uniprot.org/uniprot/HXPB_ECOLI HXPB_ECOLI] Sugar-phosphate phosphohydrolase that catalyzes the dephosphorylation of D-mannitol 1-phosphate and D-sorbitol 6-phosphate (PubMed:27941785). Also catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate (2dGlu6P); this is a biologically important activity in vivo since it contributes to the elimination of this toxic compound and plays an important role in the resistance of E.coli to 2-deoxyglucose (PubMed:16990279). To a lesser extent, is also able to dephosphorylate mannose 6-phosphate (Man6P), erythrose-4-phosphate, 2-deoxyribose-5-phosphate (2dRib5P), ribose-5-phosphate (Rib5P) and glucose-6-phosphate (Glu6P) in vitro (PubMed:16990279).<ref>PMID:15808744</ref> <ref>PMID:16990279</ref> <ref>PMID:27941785</ref>
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[[Category: Evdokimova, E.]]
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== Evolutionary Conservation ==
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[[Category: Joachimiak, A.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Kim, Y.]]
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Check<jmol>
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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<jmolCheckbox>
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[[Category: Savchenko, A.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/te/1te2_consurf.spt"</scriptWhenChecked>
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[[Category: Hydrolase]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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[[Category: Mcsg]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Midwest center for structural genomic]]
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</jmolCheckbox>
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[[Category: Phosphatase]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1te2 ConSurf].
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[[Category: Phosphate]]
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<div style="clear:both"></div>
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[[Category: Protein structure initiative]]
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== References ==
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[[Category: Psi]]
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<references/>
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[[Category: Structural genomic]]
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
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[[Category: Edwards A]]
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[[Category: Evdokimova E]]
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[[Category: Joachimiak A]]
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[[Category: Kim Y]]
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[[Category: Savchenko A]]

Current revision

Putative Phosphatase Ynic from Escherichia coli K12

PDB ID 1te2

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