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1xbz

From Proteopedia

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[[Image:1xbz.png|left|200px]]
 
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{{STRUCTURE_1xbz| PDB=1xbz | SCENE= }}
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==Crystal structure of 3-keto-L-gulonate 6-phosphate decarboxylase E112D/R139V/T169A mutant with bound L-xylulose 5-phosphate==
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<StructureSection load='1xbz' size='340' side='right'caption='[[1xbz]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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===Crystal structure of 3-keto-L-gulonate 6-phosphate decarboxylase E112D/R139V/T169A mutant with bound L-xylulose 5-phosphate===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1xbz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XBZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XBZ FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15697207}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LX1:L-XYLULOSE+5-PHOSPHATE'>LX1</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xbz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xbz OCA], [https://pdbe.org/1xbz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xbz RCSB], [https://www.ebi.ac.uk/pdbsum/1xbz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xbz ProSAT]</span></td></tr>
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[[1xbz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XBZ OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/ULAD_ECOLI ULAD_ECOLI] Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. Is involved in the anaerobic L-ascorbate utilization.<ref>PMID:11741871</ref>
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<ref group="xtra">PMID:015697207</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xb/1xbz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xbz ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Akana, J.]]
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[[Category: Large Structures]]
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[[Category: Gerlt, J A.]]
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[[Category: Akana J]]
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[[Category: Rayment, I.]]
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[[Category: Gerlt JA]]
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[[Category: Wise, E L.]]
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[[Category: Rayment I]]
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[[Category: Yew, W S.]]
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[[Category: Wise EL]]
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[[Category: Tim barrel]]
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[[Category: Yew WS]]
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[[Category: Unknown function]]
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Current revision

Crystal structure of 3-keto-L-gulonate 6-phosphate decarboxylase E112D/R139V/T169A mutant with bound L-xylulose 5-phosphate

PDB ID 1xbz

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