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1u7o

From Proteopedia

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[[Image:1u7o.png|left|200px]]
 
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{{STRUCTURE_1u7o| PDB=1u7o | SCENE= }}
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==Magnesium Dependent Phosphatase 1 (MDP-1)==
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<StructureSection load='1u7o' size='340' side='right'caption='[[1u7o]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===Magnesium Dependent Phosphatase 1 (MDP-1)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1u7o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U7O FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15461449}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u7o OCA], [https://pdbe.org/1u7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u7o RCSB], [https://www.ebi.ac.uk/pdbsum/1u7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u7o ProSAT]</span></td></tr>
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[[1u7o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U7O OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/MGDP1_MOUSE MGDP1_MOUSE] Magnesium-dependent phosphatase which may act as a tyrosine phosphatase.<ref>PMID:10889041</ref> <ref>PMID:11601995</ref> <ref>PMID:15461449</ref>
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<ref group="xtra">PMID:015461449</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u7/1u7o_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u7o ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Allen, K N.]]
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[[Category: Allen KN]]
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[[Category: Dunaway-Mariano, D.]]
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[[Category: Dunaway-Mariano D]]
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[[Category: Peisach, E.]]
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[[Category: Peisach E]]
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[[Category: Selengut, J D.]]
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[[Category: Selengut JD]]
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[[Category: Aspartate nucleophile]]
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[[Category: Class iii]]
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[[Category: Enzyme evolution]]
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[[Category: Had superfamily]]
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[[Category: Hydrolase]]
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[[Category: Phosphoryl transfer]]
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[[Category: Phosphotyrosine phosphatase]]
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[[Category: Structural enzymology]]
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Current revision

Magnesium Dependent Phosphatase 1 (MDP-1)

PDB ID 1u7o

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