1vr3
From Proteopedia
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| - | [[Image:1vr3.png|left|200px]] | ||
| - | + | ==Crystal structure of Acireductone dioxygenase (13543033) from Mus musculus at 2.06 A resolution== | |
| - | + | <StructureSection load='1vr3' size='340' side='right'caption='[[1vr3]], [[Resolution|resolution]] 2.06Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1vr3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VR3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VR3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.06Å</td></tr> | |
| - | == | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> |
| - | [[1vr3]] is a 1 chain structure with sequence from [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vr3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vr3 OCA], [https://pdbe.org/1vr3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vr3 RCSB], [https://www.ebi.ac.uk/pdbsum/1vr3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vr3 ProSAT], [https://www.topsan.org/Proteins/JCSG/1vr3 TOPSAN]</span></td></tr> |
| - | + | </table> | |
| - | == | + | == Function == |
| - | < | + | [https://www.uniprot.org/uniprot/MTND_MOUSE MTND_MOUSE] Catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14 (By similarity).[HAMAP-Rule:MF_03154] |
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vr/1vr3_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vr3 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: JCSG, Joint Center for Structural Genomics.]] | ||
| - | [[Category: 13543033]] | ||
| - | [[Category: Acireductone dioxygenase]] | ||
| - | [[Category: Jcsg]] | ||
| - | [[Category: Joint center for structural genomic]] | ||
| - | [[Category: Oxidoreductase]] | ||
| - | [[Category: Protein structure initiative]] | ||
| - | [[Category: Psi]] | ||
| - | [[Category: Structural genomic]] | ||
Current revision
Crystal structure of Acireductone dioxygenase (13543033) from Mus musculus at 2.06 A resolution
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