1u5o
From Proteopedia
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| - | [[Image:1u5o.png|left|200px]] | ||
| - | + | ==Structure of the D23A mutant of the nuclear transport carrier NTF2== | |
| - | + | <StructureSection load='1u5o' size='340' side='right'caption='[[1u5o]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1u5o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U5O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U5O FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u5o OCA], [https://pdbe.org/1u5o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u5o RCSB], [https://www.ebi.ac.uk/pdbsum/1u5o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u5o ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1u5o]] is a 2 chain structure with sequence from [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/NTF2_RAT NTF2_RAT] Facilitates protein transport into the nucleus. Interacts with the nucleoporin p62 and with Ran. Acts at a relatively late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import (By similarity). | |
| - | == | + | == Evolutionary Conservation == |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u5/1u5o_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u5o ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| - | [[Category: Bowman | + | [[Category: Bowman BR]] |
| - | [[Category: Cushman | + | [[Category: Cushman I]] |
| - | [[Category: Lichtarge | + | [[Category: Lichtarge O]] |
| - | [[Category: Moore | + | [[Category: Moore MS]] |
| - | [[Category: Quiocho | + | [[Category: Quiocho FA]] |
| - | [[Category: Sowa | + | [[Category: Sowa ME]] |
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Current revision
Structure of the D23A mutant of the nuclear transport carrier NTF2
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