This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1y5y

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:55, 14 February 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1y5y.png|left|200px]]
 
-
{{STRUCTURE_1y5y| PDB=1y5y | SCENE= }}
+
==Structure of the tetrahydromethanopterin dependent formaldehyde-activating enzyme (Fae) from Methylobacterium extorquens AM1==
-
 
+
<StructureSection load='1y5y' size='340' side='right'caption='[[1y5y]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
===Structure of the tetrahydromethanopterin dependent formaldehyde-activating enzyme (Fae) from Methylobacterium extorquens AM1===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1y5y]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Methylorubrum_extorquens_AM1 Methylorubrum extorquens AM1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y5Y FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_15632161}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y5y OCA], [https://pdbe.org/1y5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y5y RCSB], [https://www.ebi.ac.uk/pdbsum/1y5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y5y ProSAT]</span></td></tr>
-
[[1y5y]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Methylobacterium_extorquens Methylobacterium extorquens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y5Y OCA].
+
</table>
-
 
+
== Function ==
-
==Reference==
+
[https://www.uniprot.org/uniprot/FAE_METEA FAE_METEA] Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10-methylenetetrahydromethanopterin, a reaction which also proceeds spontaneously, but at a lower rate than that of the enzyme-catalyzed reaction. Is an essential enzyme for methylotrophic energy metabolism and formaldehyde detoxification of this bacterium.<ref>PMID:11073907</ref> <ref>PMID:15632161</ref>
-
<ref group="xtra">PMID:015632161</ref><references group="xtra"/>
+
== Evolutionary Conservation ==
-
[[Category: Methylobacterium extorquens]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Acharya, P.]]
+
Check<jmol>
-
[[Category: Demmer, U.]]
+
<jmolCheckbox>
-
[[Category: Ermler, U.]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/y5/1y5y_consurf.spt"</scriptWhenChecked>
-
[[Category: Goenrich, M.]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Hagemeier, C H.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Thauer, R K.]]
+
</jmolCheckbox>
-
[[Category: Vorholt, J A.]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1y5y ConSurf].
-
[[Category: Beta-alpha-beta left handed crossover]]
+
<div style="clear:both"></div>
-
[[Category: Flexible c-terminus]]
+
== References ==
-
[[Category: Lyase]]
+
<references/>
-
[[Category: Pentamer]]
+
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Methylorubrum extorquens AM1]]
 +
[[Category: Acharya P]]
 +
[[Category: Demmer U]]
 +
[[Category: Ermler U]]
 +
[[Category: Goenrich M]]
 +
[[Category: Hagemeier CH]]
 +
[[Category: Thauer RK]]
 +
[[Category: Vorholt JA]]

Current revision

Structure of the tetrahydromethanopterin dependent formaldehyde-activating enzyme (Fae) from Methylobacterium extorquens AM1

PDB ID 1y5y

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1y5y"
Personal tools