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1tlw

From Proteopedia

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[[Image:1tlw.png|left|200px]]
 
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{{STRUCTURE_1tlw| PDB=1tlw | SCENE= }}
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==Tsx structure complexed with thymidine==
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<StructureSection load='1tlw' size='340' side='right'caption='[[1tlw]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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===Tsx structure complexed with thymidine===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1tlw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TLW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TLW FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15272310}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=THM:THYMIDINE'>THM</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tlw OCA], [https://pdbe.org/1tlw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tlw RCSB], [https://www.ebi.ac.uk/pdbsum/1tlw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tlw ProSAT]</span></td></tr>
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[[1tlw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TLW OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/TSX_ECOLI TSX_ECOLI] Constitutes the receptor for colicin K and phage T6, and functions as substrate-specific channel for nucleosides and deoxynucleosides.
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<ref group="xtra">PMID:015272310</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tl/1tlw_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tlw ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Berg, B van den.]]
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[[Category: Large Structures]]
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[[Category: Ye, J.]]
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[[Category: Ye J]]
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[[Category: Beta barrel]]
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[[Category: Van den Berg B]]
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[[Category: Membrane protein]]
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[[Category: Nucleoside transporter]]
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[[Category: Thymidine]]
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Current revision

Tsx structure complexed with thymidine

PDB ID 1tlw

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