1t3e

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[[Image:1t3e.png|left|200px]]
 
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{{STRUCTURE_1t3e| PDB=1t3e | SCENE= }}
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==Structural basis of dynamic glycine receptor clustering==
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<StructureSection load='1t3e' size='340' side='right'caption='[[1t3e]], [[Resolution|resolution]] 3.25&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1t3e]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T3E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T3E FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.25&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t3e OCA], [https://pdbe.org/1t3e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t3e RCSB], [https://www.ebi.ac.uk/pdbsum/1t3e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t3e ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GEPH_RAT GEPH_RAT] Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.<ref>PMID:8264797</ref> <ref>PMID:9990024</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t3/1t3e_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t3e ConSurf].
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<div style="clear:both"></div>
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===Structural basis of dynamic glycine receptor clustering===
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==See Also==
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*[[Gephyrin|Gephyrin]]
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{{ABSTRACT_PUBMED_15201864}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[1t3e]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T3E OCA].
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</StructureSection>
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[[Category: Large Structures]]
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==Reference==
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<ref group="xtra">PMID:015201864</ref><references group="xtra"/>
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[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Bavro, V N.]]
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[[Category: Bavro VN]]
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[[Category: Franz, T.]]
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[[Category: Franz T]]
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[[Category: Paarmann, I.]]
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[[Category: O'Sullivan GA]]
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[[Category: Ricard-Blum, S.]]
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[[Category: Paarmann I]]
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[[Category: Ruigrok, R W.H.]]
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[[Category: Ricard-Blum S]]
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[[Category: Saiyed, T.]]
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[[Category: Ruigrok RWH]]
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[[Category: Schoehn, G.]]
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[[Category: Saiyed T]]
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[[Category: Sola, M.]]
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[[Category: Schoehn G]]
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[[Category: Sullivan, G A.O.]]
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[[Category: Sola M]]
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[[Category: Timmins, J.]]
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[[Category: Timmins J]]
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[[Category: Alfa-beta]]
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[[Category: Structural protein-signaling protein complex]]
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Current revision

Structural basis of dynamic glycine receptor clustering

PDB ID 1t3e

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