1u2e
From Proteopedia
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| - | [[Image:1u2e.png|left|200px]] | ||
| - | + | ==Crystal Structure of the C-C bond hydrolase MhpC== | |
| - | + | <StructureSection load='1u2e' size='340' side='right'caption='[[1u2e]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1u2e]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U2E FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u2e OCA], [https://pdbe.org/1u2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u2e RCSB], [https://www.ebi.ac.uk/pdbsum/1u2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u2e ProSAT]</span></td></tr> |
| - | [[1u2e]] is a 4 chain structure with sequence from [ | + | </table> |
| - | + | == Function == | |
| - | == | + | [https://www.uniprot.org/uniprot/MHPC_ECOLI MHPC_ECOLI] Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6-oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid. MhpC shows some selectivity for the carboxylate of the side chain.<ref>PMID:9098055</ref> <ref>PMID:9315862</ref> |
| - | < | + | == Evolutionary Conservation == |
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u2/1u2e_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u2e ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Bugg | + | [[Category: Large Structures]] |
| - | [[Category: Coker | + | [[Category: Bugg TDH]] |
| - | [[Category: Dunn | + | [[Category: Coker A]] |
| - | [[Category: Garcia | + | [[Category: Dunn G]] |
| - | [[Category: Mohammed | + | [[Category: Garcia J-L]] |
| - | [[Category: Montgomery | + | [[Category: Mohammed F]] |
| - | [[Category: Robertson | + | [[Category: Montgomery MG]] |
| - | [[Category: Wood | + | [[Category: Robertson T]] |
| - | + | [[Category: Wood SP]] | |
| - | + | ||
Current revision
Crystal Structure of the C-C bond hydrolase MhpC
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Categories: Escherichia coli | Large Structures | Bugg TDH | Coker A | Dunn G | Garcia J-L | Mohammed F | Montgomery MG | Robertson T | Wood SP
