1wue
From Proteopedia
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| - | [[Image:1wue.png|left|200px]] | ||
| - | + | ==Crystal structure of protein GI:29375081, unknown member of enolase superfamily from enterococcus faecalis V583== | |
| + | <StructureSection load='1wue' size='340' side='right'caption='[[1wue]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1wue]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis_V583 Enterococcus faecalis V583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WUE FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wue FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wue OCA], [https://pdbe.org/1wue PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wue RCSB], [https://www.ebi.ac.uk/pdbsum/1wue PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wue ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1wue TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MENC_ENTFA MENC_ENTFA] Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:24872444). Also acts as a N-succinylamino acid racemase (NSAR) that catalyzes the racemization of N-succinyl-L-phenylglycine (PubMed:24872444). Since the gene is encoded in a menaquinone synthesis operon, OSB synthase is probably the physiological activity. A pathway that requires NSAR activity has not been identified in this species, so whether NSAR is also a biological activity is unknown (PubMed:24872444).<ref>PMID:24872444</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wu/1wue_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wue ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Mandelate racemase/muconate lactonizing enzyme 3D structures|Mandelate racemase/muconate lactonizing enzyme 3D structures]] | |
| - | + | == References == | |
| - | == | + | <references/> |
| - | [[ | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Almo | + | [[Category: Enterococcus faecalis V583]] |
| - | [[Category: Burley | + | [[Category: Large Structures]] |
| - | [[Category: Fedorov | + | [[Category: Almo SC]] |
| - | [[Category: Fedorov | + | [[Category: Burley SK]] |
| - | [[Category: Gerlt | + | [[Category: Fedorov AA]] |
| - | + | [[Category: Fedorov EV]] | |
| - | [[Category: Yew | + | [[Category: Gerlt JA]] |
| - | + | [[Category: Yew WS]] | |
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Current revision
Crystal structure of protein GI:29375081, unknown member of enolase superfamily from enterococcus faecalis V583
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