1yib

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[[Image:1yib.png|left|200px]]
 
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{{STRUCTURE_1yib| PDB=1yib | SCENE= }}
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==Crystal Structure of the Human EB1 C-terminal Dimerization Domain==
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<StructureSection load='1yib' size='340' side='right'caption='[[1yib]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1yib]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YIB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YIB FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yib OCA], [https://pdbe.org/1yib PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yib RCSB], [https://www.ebi.ac.uk/pdbsum/1yib PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yib ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MARE1_HUMAN MARE1_HUMAN] Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.<ref>PMID:12388762</ref> <ref>PMID:21646404</ref> <ref>PMID:16109370</ref> <ref>PMID:19632184</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yi/1yib_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yib ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of the Human EB1 C-terminal Dimerization Domain===
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==See Also==
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*[[End-binding protein|End-binding protein]]
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{{ABSTRACT_PUBMED_15699215}}
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*[[Microtubule-associated protein 3D structures|Microtubule-associated protein 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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[[1yib]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YIB OCA].
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__TOC__
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:015699215</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Elliott, S L.]]
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[[Category: Large Structures]]
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[[Category: Kolodziej, P A.]]
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[[Category: Elliott SL]]
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[[Category: Ohkura, H.]]
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[[Category: Kolodziej PA]]
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[[Category: Rogers, S L.]]
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[[Category: Ohkura H]]
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[[Category: Slep, K C.]]
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[[Category: Rogers SL]]
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[[Category: Vale, R D.]]
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[[Category: Slep KC]]
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[[Category: Coiled coil]]
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[[Category: Vale RD]]
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[[Category: Four helix bundle]]
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[[Category: Structural protein]]
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Current revision

Crystal Structure of the Human EB1 C-terminal Dimerization Domain

PDB ID 1yib

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