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1zmp

From Proteopedia

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[[Image:1zmp.png|left|200px]]
 
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{{STRUCTURE_1zmp| PDB=1zmp | SCENE= }}
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==Crystal structure of human defensin-5==
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<StructureSection load='1zmp' size='340' side='right'caption='[[1zmp]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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===Crystal structure of human defensin-5===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1zmp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZMP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZMP FirstGlance]. <br>
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{{ABSTRACT_PUBMED_17088326}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zmp OCA], [https://pdbe.org/1zmp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zmp RCSB], [https://www.ebi.ac.uk/pdbsum/1zmp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zmp ProSAT]</span></td></tr>
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[[1zmp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZMP OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DEF5_HUMAN DEF5_HUMAN] Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing.<ref>PMID:12021776</ref> <ref>PMID:15616305</ref> <ref>PMID:17088326</ref>
==See Also==
==See Also==
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*[[Defensin|Defensin]]
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*[[Defensin 3D structures|Defensin 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:017088326</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Lu, W.]]
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[[Category: Large Structures]]
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[[Category: Lubkowski, J.]]
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[[Category: Lu W]]
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[[Category: Szyk, A.]]
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[[Category: Lubkowski J]]
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[[Category: Antimicrobial]]
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[[Category: Szyk A]]
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[[Category: Antimicrobial protein]]
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[[Category: Human alpha-defensin]]
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[[Category: Intestinal defensin]]
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[[Category: Paneth cells defensin]]
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Current revision

Crystal structure of human defensin-5

PDB ID 1zmp

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