1yis
From Proteopedia
(Difference between revisions)
m (Protected "1yis" [edit=sysop:move=sysop]) |
|||
| (7 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:1yis.png|left|200px]] | ||
| - | + | ==Structural genomics of Caenorhabditis elegans: adenylosuccinate lyase== | |
| + | <StructureSection load='1yis' size='340' side='right'caption='[[1yis]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1yis]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YIS FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yis OCA], [https://pdbe.org/1yis PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yis RCSB], [https://www.ebi.ac.uk/pdbsum/1yis PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yis ProSAT], [https://www.topsan.org/Proteins/SECSG/1yis TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PUR8_CAEEL PUR8_CAEEL] Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yi/1yis_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yis ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Adenylosuccinate lyase 3D structures|Adenylosuccinate lyase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | [[ | + | |
| - | + | ||
[[Category: Caenorhabditis elegans]] | [[Category: Caenorhabditis elegans]] | ||
| - | [[Category: An | + | [[Category: Large Structures]] |
| - | [[Category: Arabshahi | + | [[Category: An J]] |
| - | [[Category: Bray | + | [[Category: Arabshahi A]] |
| - | [[Category: Cao | + | [[Category: Bray T]] |
| - | [[Category: Chen | + | [[Category: Cao Z]] |
| - | [[Category: Delucas | + | [[Category: Chen Y-J]] |
| - | [[Category: Gray | + | [[Category: Delucas L]] |
| - | [[Category: Huang | + | [[Category: Gray R]] |
| - | [[Category: Johnson | + | [[Category: Huang W]] |
| - | [[Category: Karpova | + | [[Category: Johnson D]] |
| - | [[Category: Li | + | [[Category: Karpova E]] |
| - | [[Category: Lu | + | [[Category: Li S]] |
| - | [[Category: Luan | + | [[Category: Lu S]] |
| - | [[Category: Luo | + | [[Category: Luan C-H]] |
| - | [[Category: Luo | + | [[Category: Luo D]] |
| - | [[Category: McKinstry | + | [[Category: Luo M]] |
| - | [[Category: Qiu | + | [[Category: McKinstry A]] |
| - | + | [[Category: Qiu S]] | |
| - | [[Category: Schormann | + | [[Category: Schormann N]] |
| - | [[Category: Shang | + | [[Category: Shang Q]] |
| - | [[Category: Symersky | + | [[Category: Symersky J]] |
| - | [[Category: Tsao | + | [[Category: Tsao J]] |
| - | [[Category: Zhang | + | [[Category: Zhang Y]] |
| - | [[Category: Zhou | + | [[Category: Zhou J]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Structural genomics of Caenorhabditis elegans: adenylosuccinate lyase
| |||||||||||
Categories: Caenorhabditis elegans | Large Structures | An J | Arabshahi A | Bray T | Cao Z | Chen Y-J | Delucas L | Gray R | Huang W | Johnson D | Karpova E | Li S | Lu S | Luan C-H | Luo D | Luo M | McKinstry A | Qiu S | Schormann N | Shang Q | Symersky J | Tsao J | Zhang Y | Zhou J

