1yqq

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[[Image:1yqq.png|left|200px]]
 
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{{STRUCTURE_1yqq| PDB=1yqq | SCENE= }}
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==Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene==
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<StructureSection load='1yqq' size='340' side='right'caption='[[1yqq]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1yqq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YQQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YQQ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GUN:GUANINE'>GUN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yqq OCA], [https://pdbe.org/1yqq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yqq RCSB], [https://www.ebi.ac.uk/pdbsum/1yqq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yqq ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/XAPA_ECOLI XAPA_ECOLI] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. This protein can degrade all purine nucleosides including xanthosine, inosine and guanosine, but cannot cleave adenosine, deoxyadenosine or hypoxanthine arabinoside. Has a preference for the neutral over the monoanionic form of xanthosine.<ref>PMID:7007808</ref> <ref>PMID:7007809</ref> <ref>PMID:3042752</ref> <ref>PMID:15808857</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yq/1yqq_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yqq ConSurf].
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<div style="clear:both"></div>
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===Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene===
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==See Also==
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*[[Purine nucleoside phosphorylase 3D structures|Purine nucleoside phosphorylase 3D structures]]
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{{ABSTRACT_PUBMED_15808857}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[1yqq]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YQQ OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:015808857</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Purine-nucleoside phosphorylase]]
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[[Category: Large Structures]]
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[[Category: Bochtler, M.]]
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[[Category: Bochtler M]]
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[[Category: Dandanell, G.]]
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[[Category: Dandanell G]]
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[[Category: Kierdaszuk, B.]]
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[[Category: Kierdaszuk B]]
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[[Category: Shugar, D.]]
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[[Category: Shugar D]]
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[[Category: Szczepanowski, R H.]]
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[[Category: Szczepanowski RH]]
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[[Category: Guanine]]
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[[Category: Purine nucleoside phosphorylase]]
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[[Category: Transferase]]
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[[Category: Xanthine]]
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Current revision

Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene

PDB ID 1yqq

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