2cyf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:45, 13 March 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2cyf.png|left|200px]]
 
-
{{STRUCTURE_2cyf| PDB=2cyf | SCENE= }}
+
==The Crystal Structure of Canavalia Maritima Lectin (ConM) in Complex with Trehalose and Maltose==
 +
<StructureSection load='2cyf' size='340' side='right'caption='[[2cyf]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2cyf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Canavalia_rosea Canavalia rosea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CYF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CYF FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cyf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cyf OCA], [https://pdbe.org/2cyf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cyf RCSB], [https://www.ebi.ac.uk/pdbsum/2cyf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cyf ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CONA_CANBR CONA_CANBR] Glucose/D-mannose specific lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from hamster and rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 20 ug/ml.<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:8891754</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cy/2cyf_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cyf ConSurf].
 +
<div style="clear:both"></div>
-
===The Crystal Structure of Canavalia Maritima Lectin (ConM) in Complex with Trehalose and Maltose===
+
==See Also==
-
 
+
*[[Concanavalin 3D structures|Concanavalin 3D structures]]
-
{{ABSTRACT_PUBMED_16677825}}
+
== References ==
-
 
+
<references/>
-
==About this Structure==
+
__TOC__
-
[[2cyf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_rosea Canavalia rosea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CYF OCA].
+
</StructureSection>
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:016677825</ref><references group="xtra"/>
+
[[Category: Canavalia rosea]]
[[Category: Canavalia rosea]]
-
[[Category: Azevedo, W F.]]
+
[[Category: Large Structures]]
-
[[Category: Cavada, B S.]]
+
[[Category: Azevedo Jr WF]]
-
[[Category: Delatorre, P.]]
+
[[Category: Cavada BS]]
-
[[Category: Gadelha, C A.A.]]
+
[[Category: Delatorre P]]
-
[[Category: Rocha, B A.M.]]
+
[[Category: Gadelha CAA]]
-
[[Category: Sousa, E P.]]
+
[[Category: Rocha BAM]]
-
[[Category: Canacalia maritima]]
+
[[Category: Sousa EP]]
-
[[Category: Lectin]]
+
-
[[Category: Maltose]]
+
-
[[Category: Metal binding protein]]
+

Current revision

The Crystal Structure of Canavalia Maritima Lectin (ConM) in Complex with Trehalose and Maltose

PDB ID 2cyf

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2cyf"
Personal tools