This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2e3s

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2e3s" [edit=sysop:move=sysop])
Current revision (13:48, 13 March 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2e3s.png|left|200px]]
 
-
{{STRUCTURE_2e3s| PDB=2e3s | SCENE= }}
+
==Crystal structure of CERT START domain co-crystallized with C24-ceramide (P21)==
-
 
+
<StructureSection load='2e3s' size='340' side='right'caption='[[2e3s]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
-
===Crystal structure of CERT START domain co-crystallized with C24-ceramide (P21)===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2e3s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E3S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E3S FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_18184806}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e3s OCA], [https://pdbe.org/2e3s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e3s RCSB], [https://www.ebi.ac.uk/pdbsum/2e3s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e3s ProSAT]</span></td></tr>
-
==About this Structure==
+
</table>
-
[[2e3s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E3S OCA].
+
== Disease ==
-
 
+
[https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] The disease is caused by variants affecting the gene represented in this entry.
-
==Reference==
+
== Function ==
-
<ref group="xtra">PMID:018184806</ref><references group="xtra"/>
+
[https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.<ref>PMID:14685229</ref> <ref>PMID:17591919</ref> <ref>PMID:18184806</ref> <ref>PMID:20036255</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e3/2e3s_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e3s ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Hanada, K.]]
+
[[Category: Large Structures]]
-
[[Category: Kato, R.]]
+
[[Category: Hanada K]]
-
[[Category: Kudo, N.]]
+
[[Category: Kato R]]
-
[[Category: Kumagai, K.]]
+
[[Category: Kudo N]]
-
[[Category: Nishijima, M.]]
+
[[Category: Kumagai K]]
-
[[Category: Wakatsuki, S.]]
+
[[Category: Nishijima M]]
-
[[Category: Ceramide transfer]]
+
[[Category: Wakatsuki S]]
-
[[Category: Cert]]
+
-
[[Category: Lipid transfer protein]]
+
-
[[Category: Lipid transport]]
+

Current revision

Crystal structure of CERT START domain co-crystallized with C24-ceramide (P21)

PDB ID 2e3s

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2e3s"
Personal tools