This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2b26
From Proteopedia
(Difference between revisions)
m (Protected "2b26" [edit=sysop:move=sysop]) |
|||
| (7 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2b26.png|left|200px]] | ||
| - | + | ==The crystal structure of the protein complex of yeast Hsp40 Sis1 and Hsp70 Ssa1== | |
| - | + | <StructureSection load='2b26' size='340' side='right'caption='[[2b26]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2b26]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B26 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B26 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b26 OCA], [https://pdbe.org/2b26 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b26 RCSB], [https://www.ebi.ac.uk/pdbsum/2b26 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b26 ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[2b26]] is a 4 chain structure with sequence from [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/SIS1_YEAST SIS1_YEAST] Required for nuclear migration during mitosis. It is required for the normal initiation of translation. Might mediate the dissociation of a specific protein complex of the translation machinery. Essential for viability. | |
| - | == | + | == Evolutionary Conservation == |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b2/2b26_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b26 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | [[Category: Li | + | [[Category: Li J]] |
| - | [[Category: Qian | + | [[Category: Qian X]] |
| - | [[Category: Sha | + | [[Category: Sha B]] |
| - | [[Category: Wu | + | [[Category: Wu Y]] |
| - | + | ||
| - | + | ||
Current revision
The crystal structure of the protein complex of yeast Hsp40 Sis1 and Hsp70 Ssa1
| |||||||||||

