2d2p
From Proteopedia
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- | [[Image:2d2p.png|left|200px]] | ||
- | + | ==The solution structure of micelle-bound peptide== | |
- | + | <StructureSection load='2d2p' size='340' side='right'caption='[[2d2p]]' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2d2p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D2P FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> | |
- | == | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> |
- | [[2d2p]] is a 1 chain structure with sequence from [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d2p OCA], [https://pdbe.org/2d2p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d2p RCSB], [https://www.ebi.ac.uk/pdbsum/2d2p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d2p ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/PACA_HUMAN PACA_HUMAN] Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells.<ref>PMID:11175907</ref> | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d2/2d2p_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d2p ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Hiroaki | + | [[Category: Large Structures]] |
- | [[Category: Inooka | + | [[Category: Hiroaki H]] |
- | [[Category: Jee | + | [[Category: Inooka H]] |
- | [[Category: Shirakawa | + | [[Category: Jee JG]] |
- | [[Category: Tateishi | + | [[Category: Shirakawa M]] |
- | [[Category: Tochio | + | [[Category: Tateishi Y]] |
- | + | [[Category: Tochio H]] |
Current revision
The solution structure of micelle-bound peptide
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Categories: Homo sapiens | Large Structures | Hiroaki H | Inooka H | Jee JG | Shirakawa M | Tateishi Y | Tochio H