2d3w
From Proteopedia
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- | [[Image:2d3w.png|left|200px]] | ||
- | + | ==Crystal Structure of Escherichia coli SufC, an ATPase compenent of the SUF iron-sulfur cluster assembly machinery== | |
- | + | <StructureSection load='2d3w' size='340' side='right'caption='[[2d3w]], [[Resolution|resolution]] 2.50Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2d3w]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D3W FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d3w OCA], [https://pdbe.org/2d3w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d3w RCSB], [https://www.ebi.ac.uk/pdbsum/2d3w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d3w ProSAT]</span></td></tr> | |
- | == | + | </table> |
- | [[2d3w]] is a 4 chain structure with sequence from [ | + | == Function == |
- | + | [https://www.uniprot.org/uniprot/SUFC_ECOLI SUFC_ECOLI] Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation.<ref>PMID:12554644</ref> <ref>PMID:12941942</ref> | |
- | == | + | == Evolutionary Conservation == |
- | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d3/2d3w_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d3w ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
- | [[Category: Fukuyama | + | [[Category: Large Structures]] |
- | [[Category: Hasegawa | + | [[Category: Fukuyama K]] |
- | [[Category: Kitaoka | + | [[Category: Hasegawa Y]] |
- | [[Category: Minami | + | [[Category: Kitaoka S]] |
- | [[Category: Takahashi | + | [[Category: Minami Y]] |
- | [[Category: Wada | + | [[Category: Takahashi Y]] |
- | + | [[Category: Wada K]] | |
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Current revision
Crystal Structure of Escherichia coli SufC, an ATPase compenent of the SUF iron-sulfur cluster assembly machinery
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