2b05

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[[Image:2b05.png|left|200px]]
 
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{{STRUCTURE_2b05| PDB=2b05 | SCENE= }}
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==Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide==
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<StructureSection load='2b05' size='340' side='right'caption='[[2b05]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2b05]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B05 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B05 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b05 OCA], [https://pdbe.org/2b05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b05 RCSB], [https://www.ebi.ac.uk/pdbsum/2b05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b05 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/1433G_HUMAN 1433G_HUMAN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.<ref>PMID:16511572</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b0/2b05_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b05 ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide===
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==See Also==
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*[[14-3-3 protein 3D structures|14-3-3 protein 3D structures]]
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{{ABSTRACT_PUBMED_017085597}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[2b05]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B05 OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:017085597</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C.]]
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[[Category: Large Structures]]
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[[Category: Debreczeni, E J.]]
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[[Category: Arrowsmith C]]
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[[Category: Delft, F von.]]
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[[Category: Debreczeni EJ]]
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[[Category: Doyle, D.]]
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[[Category: Doyle D]]
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[[Category: Edwards, A.]]
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[[Category: Edwards A]]
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[[Category: Elkins, J.]]
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[[Category: Elkins J]]
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[[Category: Papagrigoriou, E.]]
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[[Category: Papagrigoriou E]]
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[[Category: Turnbull, A.]]
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[[Category: Turnbull A]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt J]]
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[[Category: Yang, X.]]
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[[Category: Yang X]]
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[[Category: Zhao, Y.]]
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[[Category: Zhao Y]]
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[[Category: Cell cycle]]
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[[Category: Von Delft F]]

Current revision

Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide

PDB ID 2b05

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