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2cov

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[[Image:2cov.png|left|200px]]
 
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{{STRUCTURE_2cov| PDB=2cov | SCENE= }}
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==Crystal structure of CBM31 from beta-1,3-xylanase==
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<StructureSection load='2cov' size='340' side='right'caption='[[2cov]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2cov]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Alcaligenes_sp._XY-234 Alcaligenes sp. XY-234]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2COV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2COV FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cov FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cov OCA], [https://pdbe.org/2cov PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cov RCSB], [https://www.ebi.ac.uk/pdbsum/2cov PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cov ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/3XYN_ALCSP 3XYN_ALCSP] Catalyzes the hydrolysis of beta-1,3-xylan into oligosaccharides, mainly xylotriose and xylobiose with smaller amounts of xylotetraose, xylose, xylopentaose and xylohexaose. Does not hydrolyze xylobiose, p-nitrophenyl-beta-xyloside, beta-1,4-xylan, carboxymethylcellulose, curdlan, glucomannan or beta-1,4-mannan.<ref>PMID:11948152</ref> <ref>PMID:12501421</ref>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Here, we present the crystal structure of the family 31 carbohydrate-binding module (CBM) of beta-1,3-xylanase from Alcaligenes sp. strain XY-234 (AlcCBM31) determined at a resolution of 1.25A. The AlcCBM31 shows affinity with only beta-1,3-xylan. The AlcCBM31 molecule makes a beta-sandwich structure composed of eight beta-strands with a typical immunoglobulin fold and contains two intra-molecular disulfide bonds. The folding topology of AlcCBM31 differs from that of the large majority of other CBMs, in which eight beta-strands comprise a beta-sandwich structure with a typical jelly-roll fold. AlcCBM31 shows structural similarity with CBM structures of family 34 and family 9, which also adopt structures based on immunoglobulin folds.
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===Crystal structure of CBM31 from beta-1,3-xylanase===
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The first crystal structure of a family 31 carbohydrate-binding module with affinity to beta-1,3-xylan.,Hashimoto H, Tamai Y, Okazaki F, Tamaru Y, Shimizu T, Araki T, Sato M FEBS Lett. 2005 Aug 15;579(20):4324-8. PMID:16061225<ref>PMID:16061225</ref>
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{{ABSTRACT_PUBMED_16061225}}
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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==About this Structure==
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<div class="pdbe-citations 2cov" style="background-color:#fffaf0;"></div>
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[[2cov]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Alcaligenes_sp. Alcaligenes sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2COV OCA].
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== References ==
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[[Category: Alcaligenes sp.]]
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<references/>
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[[Category: Araki, T.]]
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__TOC__
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[[Category: Hashimoto, H.]]
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</StructureSection>
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[[Category: Okazaki, F.]]
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[[Category: Alcaligenes sp. XY-234]]
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[[Category: Sato, M.]]
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[[Category: Large Structures]]
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[[Category: Shimizu, T.]]
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[[Category: Araki T]]
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[[Category: Tamai, Y.]]
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[[Category: Hashimoto H]]
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[[Category: Tamaru, Y.]]
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[[Category: Okazaki F]]
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[[Category: 3-xylanase]]
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[[Category: Sato M]]
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[[Category: Beta-1]]
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[[Category: Shimizu T]]
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[[Category: Carbohydrate-binding module]]
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[[Category: Tamai Y]]
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[[Category: Family 31 cbm]]
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[[Category: Tamaru Y]]
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[[Category: Sugar binding protein]]
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Current revision

Crystal structure of CBM31 from beta-1,3-xylanase

PDB ID 2cov

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