1v5s
From Proteopedia
(Difference between revisions)
| (15 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:1v5s.jpg|left|200px]]<br /><applet load="1v5s" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1v5s" /> | ||
| - | '''Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3'''<br /> | ||
| - | == | + | ==Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3== |
| - | + | <StructureSection load='1v5s' size='340' side='right'caption='[[1v5s]]' scene=''> | |
| - | [ | + | == Structural highlights == |
| - | [ | + | <table><tr><td colspan='2'>[[1v5s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V5S FirstGlance]. <br> |
| - | [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v5s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v5s OCA], [https://pdbe.org/1v5s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v5s RCSB], [https://www.ebi.ac.uk/pdbsum/1v5s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v5s ProSAT], [https://www.topsan.org/Proteins/RSGI/1v5s TOPSAN]</span></td></tr> | |
| - | [ | + | </table> |
| - | [ | + | == Function == |
| - | [ | + | [https://www.uniprot.org/uniprot/MARK3_MOUSE MARK3_MOUSE] Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (By similarity). |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | + | Check<jmol> | |
| - | [[ | + | <jmolCheckbox> |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v5/1v5s_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | + | </jmolCheckbox> | |
| - | [ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v5s ConSurf]. |
| - | [[ | + | <div style="clear:both"></div> |
| - | + | ||
| - | + | ==See Also== | |
| + | *[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Inoue M]] | ||
| + | [[Category: Kigawa T]] | ||
| + | [[Category: Koshiba S]] | ||
| + | [[Category: Tochio N]] | ||
| + | [[Category: Yokoyama S]] | ||
Current revision
Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3
| |||||||||||
Categories: Large Structures | Mus musculus | Inoue M | Kigawa T | Koshiba S | Tochio N | Yokoyama S
