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1v63
From Proteopedia
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| - | [[Image:1v63.gif|left|200px]]<br /><applet load="1v63" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1v63" /> | ||
| - | '''Solution structure of the 6th HMG box of mouse UBF1'''<br /> | ||
| - | == | + | ==Solution structure of the 6th HMG box of mouse UBF1== |
| - | + | <StructureSection load='1v63' size='340' side='right'caption='[[1v63]]' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1v63]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V63 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v63 OCA], [https://pdbe.org/1v63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v63 RCSB], [https://www.ebi.ac.uk/pdbsum/1v63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v63 ProSAT], [https://www.topsan.org/Proteins/RSGI/1v63 TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/UBF1_MOUSE UBF1_MOUSE] Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.<ref>PMID:20168301</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v6/1v63_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v63 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | + | [[Category: Inoue M]] | |
| - | [[Category: Inoue | + | [[Category: Kigawa T]] |
| - | [[Category: Kigawa | + | [[Category: Koshiba S]] |
| - | [[Category: Koshiba | + | [[Category: Saito K]] |
| - | + | [[Category: Sato M]] | |
| - | [[Category: Saito | + | [[Category: Yokoyama S]] |
| - | [[Category: Sato | + | |
| - | [[Category: Yokoyama | + | |
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Current revision
Solution structure of the 6th HMG box of mouse UBF1
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Categories: Large Structures | Mus musculus | Inoue M | Kigawa T | Koshiba S | Saito K | Sato M | Yokoyama S
