2b3w

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[[Image:2b3w.png|left|200px]]
 
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{{STRUCTURE_2b3w| PDB=2b3w | SCENE= }}
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==NMR structure of the E.coli protein YbiA, Northeast Structural Genomics target ET24.==
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<StructureSection load='2b3w' size='340' side='right'caption='[[2b3w]]' scene=''>
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===NMR structure of the E.coli protein YbiA, Northeast Structural Genomics target ET24.===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2b3w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B3W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B3W FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b3w OCA], [https://pdbe.org/2b3w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b3w RCSB], [https://www.ebi.ac.uk/pdbsum/2b3w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b3w ProSAT], [https://www.topsan.org/Proteins/NESGC/2b3w TOPSAN]</span></td></tr>
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[[2b3w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B3W OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RIBX_ECOLI RIBX_ECOLI] Catalyzes the hydrolysis of the N-glycosidic bond in the first two intermediates of riboflavin biosynthesis, which are highly reactive metabolites, yielding relatively innocuous products. Thus, can divert a surplus of harmful intermediates into relatively harmless products and pre-empt the damage these intermediates would otherwise do. Helps maintain flavin levels. May act on other substrates in vivo. Has no activity against GTP, nucleoside monophosphates or ADP-ribose (PubMed:25431972). Is Required for swarming motility (PubMed:17122336).<ref>PMID:17122336</ref> <ref>PMID:25431972</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b3/2b3w_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b3w ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Acton, T B.]]
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[[Category: Large Structures]]
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[[Category: Cort, J R.]]
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[[Category: Acton TB]]
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[[Category: Kennedy, M A.]]
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[[Category: Cort JR]]
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[[Category: Montelione, G T.]]
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[[Category: Kennedy MA]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Montelione GT]]
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[[Category: Ramelot, T A.]]
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[[Category: Ramelot TA]]
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[[Category: Shih, L Y.]]
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[[Category: Shih LY]]
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[[Category: Xiao, R.]]
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[[Category: Xiao R]]
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[[Category: Cog 3236]]
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[[Category: Et24]]
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[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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[[Category: Unknown function]]
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[[Category: Ybia]]
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Current revision

NMR structure of the E.coli protein YbiA, Northeast Structural Genomics target ET24.

PDB ID 2b3w

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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