2bkf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:17, 9 May 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2bkf.png|left|200px]]
 
-
{{STRUCTURE_2bkf| PDB=2bkf | SCENE= }}
+
==Structure of the PB1 domain of NBR1==
 +
<StructureSection load='2bkf' size='340' side='right'caption='[[2bkf]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2bkf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BKF FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.56&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bkf OCA], [https://pdbe.org/2bkf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bkf RCSB], [https://www.ebi.ac.uk/pdbsum/2bkf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bkf ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/NBR1_HUMAN NBR1_HUMAN] Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets.<ref>PMID:19250911</ref>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
The scaffold protein NBR1 is involved in signal transmission downstream of the serine/protein kinase from the giant muscle protein titin. Its N-terminal Phox and Bem1p (PB1) domain plays a critical role in mediating protein-protein interactions with both titin kinase and with another scaffold protein, p62. We have determined the crystal structure of the PB1 domain of NBR1 at 1.55A resolution. It reveals a type-A PB1 domain with two negatively charged residue clusters. We provide a structural perspective on the involvement of NBR1 in the titin kinase signalling pathway.
-
===STRUCTURE OF THE PB1 DOMAIN OF NBR1===
+
Crystal structure of the PB1 domain of NBR1.,Muller S, Kursula I, Zou P, Wilmanns M FEBS Lett. 2006 Jan 9;580(1):341-4. Epub 2005 Dec 19. PMID:16376336<ref>PMID:16376336</ref>
-
{{ABSTRACT_PUBMED_16376336}}
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
 
+
</div>
-
==About this Structure==
+
<div class="pdbe-citations 2bkf" style="background-color:#fffaf0;"></div>
-
[[2bkf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BKF OCA].
+
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Kursula, I.]]
+
[[Category: Large Structures]]
-
[[Category: Mueller, S.]]
+
[[Category: Kursula I]]
-
[[Category: Wilmanns, M.]]
+
[[Category: Mueller S]]
-
[[Category: Interaction domain]]
+
[[Category: Wilmanns M]]
-
[[Category: Nbr1]]
+
-
[[Category: Pb1 domain]]
+
-
[[Category: Zinc-finger]]
+
-
[[Category: Zinc-finger protein]]
+

Current revision

Structure of the PB1 domain of NBR1

PDB ID 2bkf

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2bkf"
Personal tools