2c7i

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[[Image:2c7i.png|left|200px]]
 
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{{STRUCTURE_2c7i| PDB=2c7i | SCENE= }}
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==Structure of protein Ta0514, putative lipoate protein ligase from T. acidophilum.==
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<StructureSection load='2c7i' size='340' side='right'caption='[[2c7i]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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===STRUCTURE OF PROTEIN TA0514, PUTATIVE LIPOATE PROTEIN LIGASE FROM T. ACIDOPHILUM.===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2c7i]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoplasma_acidophilum_DSM_1728 Thermoplasma acidophilum DSM 1728]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C7I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C7I FirstGlance]. <br>
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{{ABSTRACT_PUBMED_16384580}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c7i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c7i OCA], [https://pdbe.org/2c7i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c7i RCSB], [https://www.ebi.ac.uk/pdbsum/2c7i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c7i ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[2c7i]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C7I OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/LPLAN_THEAC LPLAN_THEAC] Part of a lipoate-protein ligase complex that catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Can also use octanoate as substrate.<ref>PMID:16141198</ref> <ref>PMID:19520844</ref> <ref>PMID:19594830</ref>
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==Reference==
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== Evolutionary Conservation ==
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<ref group="xtra">PMID:016384580</ref><references group="xtra"/>
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Thermoplasma acidophilum]]
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Check<jmol>
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[[Category: Luisi, B F.]]
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<jmolCheckbox>
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[[Category: Mcmanus, E.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c7/2c7i_consurf.spt"</scriptWhenChecked>
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[[Category: Perham, R N.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Ligase]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Lipoylation]]
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c7i ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Thermoplasma acidophilum DSM 1728]]
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[[Category: Luisi BF]]
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[[Category: Mcmanus E]]
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[[Category: Perham RN]]

Current revision

Structure of protein Ta0514, putative lipoate protein ligase from T. acidophilum.

PDB ID 2c7i

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