2ay0
From Proteopedia
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| - | [[Image:2ay0.png|left|200px]] | ||
| - | + | ==Structure of the Lys9Met mutant of the E. coli Proline Utilization A (PutA) DNA-binding domain.== | |
| + | <StructureSection load='2ay0' size='340' side='right'caption='[[2ay0]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2ay0]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AY0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AY0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ay0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ay0 OCA], [https://pdbe.org/2ay0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ay0 RCSB], [https://www.ebi.ac.uk/pdbsum/2ay0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ay0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PUTA_ECOLI PUTA_ECOLI] Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ay/2ay0_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ay0 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Proline utilization A|Proline utilization A]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
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[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Becker | + | [[Category: Large Structures]] |
| - | [[Category: Jenkins | + | [[Category: Becker DF]] |
| - | [[Category: Larson | + | [[Category: Jenkins JL]] |
| - | [[Category: Schuermann | + | [[Category: Larson JD]] |
| - | [[Category: Tanner | + | [[Category: Schuermann JP]] |
| - | [[Category: Zhou | + | [[Category: Tanner JJ]] |
| - | + | [[Category: Zhou Y]] | |
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Current revision
Structure of the Lys9Met mutant of the E. coli Proline Utilization A (PutA) DNA-binding domain.
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